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Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

Interferons (IFNs) are pleotropic cytokines secreted upon encounter of pathogens and tumors. Applying their antipathogenic, antiproliferative, and immune stimulatory capacities, recombinant IFNs are frequently prescribed as drugs to treat different diseases. IFNs act by changing the gene expression...

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Detalles Bibliográficos
Autores principales:	Megger, Dominik A., Philipp, Jos, Le-Trilling, Vu Thuy Khanh, Sitek, Barbara, Trilling, Mirko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603615/ https://www.ncbi.nlm.nih.gov/pubmed/28959263 http://dx.doi.org/10.3389/fimmu.2017.01139

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