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Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance
The fungal pathogen Candida glabrata has emerged as a major health threat since it readily acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus far, cellular mechanisms promoting the emergence of resistance to multiple drug classes have not been described in t...
Autores principales: | Healey, Kelley R., Zhao, Yanan, Perez, Winder B., Lockhart, Shawn R., Sobel, Jack D., Farmakiotis, Dimitrios, Kontoyiannis, Dimitrios P., Sanglard, Dominique, Taj-Aldeen, Saad J., Alexander, Barbara D., Jimenez-Ortigosa, Cristina, Shor, Erika, Perlin, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603725/ https://www.ncbi.nlm.nih.gov/pubmed/27020939 http://dx.doi.org/10.1038/ncomms11128 |
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