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Roquin recognizes a non-canonical hexaloop structure in the 3′-UTR of Ox40

The RNA-binding protein Roquin is required to prevent autoimmunity. Roquin controls T-helper cell activation and differentiation by limiting the induced expression of costimulatory receptors such as tumor necrosis factor receptor superfamily 4 (Tnfrs4 or Ox40). A constitutive decay element (CDE) wit...

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Detalles Bibliográficos
Autores principales:	Janowski, Robert, Heinz, Gitta A., Schlundt, Andreas, Wommelsdorf, Nina, Brenner, Sven, Gruber, Andreas R., Blank, Michael, Buch, Thorsten, Buhmann, Raymund, Zavolan, Mihaela, Niessing, Dierk, Heissmeyer, Vigo, Sattler, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603727/ https://www.ncbi.nlm.nih.gov/pubmed/27010430 http://dx.doi.org/10.1038/ncomms11032

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