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Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase

The RNA-degrading exosome mediates the processing and decay of many cellular transcripts. In the yeast nucleus, the ubiquitous 10-subunit exosome core complex (Exo-9–Rrp44) functions with four conserved cofactors (Rrp6, Rrp47, Mtr4, and Mpp6). Biochemical and structural studies to date have shed ins...

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Detalles Bibliográficos
Autores principales:	Falk, Sebastian, Bonneau, Fabien, Ebert, Judith, Kögel, Alexander, Conti, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603729/ https://www.ncbi.nlm.nih.gov/pubmed/28877463 http://dx.doi.org/10.1016/j.celrep.2017.08.033

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