Cargando…

Protease-Activated Receptor-2 Deficiency Attenuates Atherosclerotic Lesion Progression and Instability in Apolipoprotein E-Deficient Mice

Inflammatory mechanisms are involved in the process of atherosclerotic plaque formation and rupture. Accumulating evidence suggests that protease-activated receptor (PAR)-2 contributes to the pathophysiology of chronic inflammation on the vasculature. To directly examine the role of PAR-2 in atheros...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuo, Pengfei, Zuo, Zhi, Zheng, Yueyue, Wang, Xin, Zhou, Qianxing, Chen, Long, Ma, Genshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603739/ https://www.ncbi.nlm.nih.gov/pubmed/28959204 http://dx.doi.org/10.3389/fphar.2017.00647

Ejemplares similares

A cyclic azapeptide ligand of the scavenger receptor CD36/SR-B2 reduces the atherosclerotic lesion progression and enhances plaque stability in apolipoprotein E-deficient mice
por: Gauvin, Jade, et al.
Publicado: (2023)

Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factor
por: Sun, Hui, et al.
Publicado: (2015)

Xyloketal B Attenuates Atherosclerotic Plaque Formation and Endothelial Dysfunction in Apolipoprotein E Deficient Mice
por: Zhao, Li-Yan, et al.
Publicado: (2015)

Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice
por: Preusch, Michael R, et al.
Publicado: (2015)

ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions
por: Mantani, Polyxeni T., et al.
Publicado: (2019)

Visfatin Destabilizes Atherosclerotic Plaques in Apolipoprotein E–Deficient Mice
por: Li, Bo, et al.
Publicado: (2016)

Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice
por: Yao, Leyi, et al.
Publicado: (2022)

Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
por: Du, Meng, et al.
Publicado: (2016)

Isoquinoline Alkaloids and Indole Alkaloids Attenuate Aortic Atherosclerosis in Apolipoprotein E Deficient Mice: A Systematic Review and Meta-Analysis
por: Zhang, Yibing, et al.
Publicado: (2018)

Atheroregressive Potential of the Treatment with a Chimeric Monoclonal Antibody against Sulfated Glycosaminoglycans on Pre-existing Lesions in Apolipoprotein E-Deficient Mice
por: Brito, Victor, et al.
Publicado: (2017)

Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse
por: Williams, Helen, et al.
Publicado: (2010)

Isoliquiritigenin Attenuates Atherogenesis in Apolipoprotein E-Deficient Mice
por: Du, Fen, et al.
Publicado: (2016)

Notoginsenoside R1 Attenuates Atherosclerotic Lesions in ApoE Deficient Mouse Model
por: Jia, Chenglin, et al.
Publicado: (2014)

Secreted IL-1Ra exerts a protective effect on atherosclerotic lesion development in apolipoprotein-E-deficient mice
por: Soussi, F, et al.
Publicado: (2003)

TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice
por: Watt, Victoria, et al.
Publicado: (2011)

Comprehensive Plasma Metabolomic Analyses of Atherosclerotic Progression Reveal Alterations in Glycerophospholipid and Sphingolipid Metabolism in Apolipoprotein E-deficient Mice
por: Dang, Vi T., et al.
Publicado: (2016)

Betaine Supplementation Attenuates S-Adenosylhomocysteine Hydrolase-Deficiency-Accelerated Atherosclerosis in Apolipoprotein E-Deficient Mice
por: Dai, Xin, et al.
Publicado: (2022)

Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban
por: Zhou, Qianxing, et al.
Publicado: (2011)

Reduced Atherosclerotic Lesion Size in P-Selectin Deficient Apolipoprotein E-Knockout Mice Fed a Chow but Not a Fat Diet
por: Bourdillon, Marie-Claude, et al.
Publicado: (2006)

Moxibustion at CV4 alleviates atherosclerotic lesions through activation of the LXRα/ABCA1 pathway in apolipoprotein-E-deficient mice
por: Cui, Yingxue, et al.
Publicado: (2019)

PAC1 deficiency reduces chondrogenesis in atherosclerotic lesions of hypercholesterolemic ApoE-deficient mice
por: Blümm, C., et al.
Publicado: (2023)

Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice
por: Liao, Jiawei, et al.
Publicado: (2020)

Pitavastatin Reduces Inflammation in Atherosclerotic Plaques in Apolipoprotein E-Deficient Mice with Late Stage Renal Disease
por: Shibasaki, Manabu, et al.
Publicado: (2015)

Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis
por: Manea, Simona-Adriana, et al.
Publicado: (2019)

Natural Killer T Cells Are Involved in Atherosclerotic Plaque Instability in Apolipoprotein-E Knockout Mice
por: Ohmura, Yoshinori, et al.
Publicado: (2021)

Oridonin attenuates the progression of atherosclerosis by inhibiting NLRP3 and activating Nrf2 in apolipoprotein E-deficient mice
por: Wang, Lei, et al.
Publicado: (2023)

Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes
por: Kanter, Jenny E., et al.
Publicado: (2020)

Danlou Tablets Inhibit Atherosclerosis in Apolipoprotein E-Deficient Mice by Inducing Macrophage Autophagy: The Role of the PI3K-Akt-mTOR Pathway
por: Liu, Chunping, et al.
Publicado: (2021)

Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice
por: Nagashima, M., et al.
Publicado: (2011)

Deficiency of AXL in Bone Marrow-Derived Cells Does Not Affect Advanced Atherosclerotic Lesion Progression
por: Subramanian, Manikandan, et al.
Publicado: (2016)

Low-Density Lipoprotein Receptor Deficiency Attenuates Neuroinflammation through the Induction of Apolipoprotein E
por: Mailleux, Jo, et al.
Publicado: (2017)

Luteolin attenuates angiotensin II-induced renal damage in apolipoprotein E-deficient mice
por: Liu, Ying-Shu, et al.
Publicado: (2021)

Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice
por: Wang, Jintao, et al.
Publicado: (2023)

Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
por: Rune, Ida, et al.
Publicado: (2018)

Interleukin-17A influences the vulnerability rather than the size of established atherosclerotic plaques in apolipoprotein E-deficient mice
por: Wang, Bo, et al.
Publicado: (2022)

α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis
por: Tian, Hao, et al.
Publicado: (2022)

DBZ (Danshensu Bingpian Zhi), a Novel Natural Compound Derivative, Attenuates Atherosclerosis in Apolipoprotein E–Deficient Mice
por: Wang, Jing, et al.
Publicado: (2017)

Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet
por: Sivak, Olena, et al.
Publicado: (2009)

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo
por: Lund, Ida K., et al.
Publicado: (2012)

Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease
por: Pastore, Mirella, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ubk9g1np03pgkhbmn6q9q6qdi7