The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by β-Arrestin1 binding with P300-Sp1 to regulate hTERT transcription

Although we previously reported that the self-renewal of leukemia-initiating cells of B-lineage acute lymphoblastic leukemia (B-ALL LICs) was regulated by β-Arrestin1, a multiple-function protein, the cellular senescence is critical for LICs fate and leukemia progress, and worthy for further investi...

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Detalles Bibliográficos
Autores principales: Liu, Shan, Liu, Haiyan, Qin, Ru, Shu, Yi, Liu, Zhidai, Zhang, Penghui, Duan, Caiwen, Hong, Dengli, Yu, Jie, Zou, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603829/
https://www.ncbi.nlm.nih.gov/pubmed/28425985
http://dx.doi.org/10.1038/cddis.2017.164

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