Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles

The application of Pd/Fe(3)O(4) nanoparticles (NPs) for the adsorption of sulfathiazole (STZ) from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe(3)O(4) NPs were synthesized using plant extract. Possible impact parameters in the extraction proc...

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Detalles Bibliográficos
Autores principales: Maham, Mehdi, Karami-Osboo, Rouhollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603855/
https://www.ncbi.nlm.nih.gov/pubmed/28979301
Descripción
Sumario:The application of Pd/Fe(3)O(4) nanoparticles (NPs) for the adsorption of sulfathiazole (STZ) from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe(3)O(4) NPs were synthesized using plant extract. Possible impact parameters in the extraction process such as magnetic adsorbents amount, extraction time, sample pH, and desorption conditions were investigated and optimized. Under the optimum conditions, the detection and quantification limits were 10 and 30 ng mL(−1), respectively. The relative standard deviation for five measurements of 100 ng mL(-1) of STZ was 5.8 %. The proposed method was used for the analysis of different urine samples, and acceptable recoveries in the range of 87.6 – 101.3% were obtained. These results indicated that biosynthesized Pd/Fe(3)O(4) NPs can be used as an efficient adsorbent for extraction of sulfathiazole from urine samples.

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