Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles

The application of Pd/Fe(3)O(4) nanoparticles (NPs) for the adsorption of sulfathiazole (STZ) from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe(3)O(4) NPs were synthesized using plant extract. Possible impact parameters in the extraction proc...

Descripción completa

Detalles Bibliográficos
Autores principales: Maham, Mehdi, Karami-Osboo, Rouhollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603855/
https://www.ncbi.nlm.nih.gov/pubmed/28979301
_version_ 1783264779870142464
author Maham, Mehdi
Karami-Osboo, Rouhollah
author_facet Maham, Mehdi
Karami-Osboo, Rouhollah
author_sort Maham, Mehdi
collection PubMed
description The application of Pd/Fe(3)O(4) nanoparticles (NPs) for the adsorption of sulfathiazole (STZ) from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe(3)O(4) NPs were synthesized using plant extract. Possible impact parameters in the extraction process such as magnetic adsorbents amount, extraction time, sample pH, and desorption conditions were investigated and optimized. Under the optimum conditions, the detection and quantification limits were 10 and 30 ng mL(−1), respectively. The relative standard deviation for five measurements of 100 ng mL(-1) of STZ was 5.8 %. The proposed method was used for the analysis of different urine samples, and acceptable recoveries in the range of 87.6 – 101.3% were obtained. These results indicated that biosynthesized Pd/Fe(3)O(4) NPs can be used as an efficient adsorbent for extraction of sulfathiazole from urine samples.
format Online
Article
Text
id pubmed-5603855
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Shaheed Beheshti University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-56038552017-10-04 Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles Maham, Mehdi Karami-Osboo, Rouhollah Iran J Pharm Res Original Article The application of Pd/Fe(3)O(4) nanoparticles (NPs) for the adsorption of sulfathiazole (STZ) from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe(3)O(4) NPs were synthesized using plant extract. Possible impact parameters in the extraction process such as magnetic adsorbents amount, extraction time, sample pH, and desorption conditions were investigated and optimized. Under the optimum conditions, the detection and quantification limits were 10 and 30 ng mL(−1), respectively. The relative standard deviation for five measurements of 100 ng mL(-1) of STZ was 5.8 %. The proposed method was used for the analysis of different urine samples, and acceptable recoveries in the range of 87.6 – 101.3% were obtained. These results indicated that biosynthesized Pd/Fe(3)O(4) NPs can be used as an efficient adsorbent for extraction of sulfathiazole from urine samples. Shaheed Beheshti University of Medical Sciences 2017 /pmc/articles/PMC5603855/ /pubmed/28979301 Text en © 2017 by School of Pharmacy Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Maham, Mehdi
Karami-Osboo, Rouhollah
Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title_full Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title_fullStr Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title_full_unstemmed Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title_short Extraction of Sulfathiazole from Urine Samples Using Biosynthesized Magnetic Nanoparticles
title_sort extraction of sulfathiazole from urine samples using biosynthesized magnetic nanoparticles
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603855/
https://www.ncbi.nlm.nih.gov/pubmed/28979301
work_keys_str_mv AT mahammehdi extractionofsulfathiazolefromurinesamplesusingbiosynthesizedmagneticnanoparticles
AT karamiosboorouhollah extractionofsulfathiazolefromurinesamplesusingbiosynthesizedmagneticnanoparticles

Ejemplares similares