Cargando…
In Silico Screening of IL-1β Production Inhibitors Using Chemometric Tools
The IL-1β plays a major role in inflammatory disorders and IL-1β production inhibitors can be used in the treatment of inflammatory and related diseases. In this study, quantitative relationships between the structures of 46 pyridazine derivatives (inhibitors of IL-1β production) and their activitie...
Autores principales: | Sakhteman, Amirhossein, Edraki, Najmeh, Hemmateenejad, Bahram, Miri, Ramin, Foroumadi, Alireza, Shafiee, Abbas, Khoshneviszadeh, Mehdi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603860/ https://www.ncbi.nlm.nih.gov/pubmed/28979306 |
Ejemplares similares
-
Design, synthesis, cytotoxicity evaluation and docking studies of 1,2,4-triazine derivatives bearing different arylidene-hydrazinyl moieties as potential mTOR inhibitors
por: Ranjbar, Sara, et al.
Publicado: (2018) -
Synthesis, biological evaluation and molecular docking analysis of vaniline–benzylidenehydrazine hybrids as potent tyrosinase inhibitors
por: Iraji, Aida, et al.
Publicado: (2020) -
Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents
por: Haghighijoo, Zahra, et al.
Publicado: (2020) -
Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study
por: Shahraki, Omolbanin, et al.
Publicado: (2017) -
Synthesis and In vitro cytotoxic activity evaluation of (E)-16-(substituted benzylidene) derivatives of dehydroepiandrosterone
por: Vosooghi, Mohsen, et al.
Publicado: (2013)