Docking, Synthesis and Anticonvulsant Activity of N-substituted Isoindoline-1,3-dione

A series of compounds related to ameltolide were studied for anticonvulsant potential in the subcutaneous pentylenetetrazol (sc Ptz) test in mice. These compounds were synthesized and characterized by TLC followed by IR and H(1)NMR. In-vivo screening data acquired indicate that most of analogs have...

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Detalles Bibliográficos
Autores principales: Iman, Maryam, Saadabadi, Atefeh, Davood, Asghar, Shafaroodi, Hamed, Nikbakht, Ali, Ansari, Abdollah, Abedini, Masood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603866/
https://www.ncbi.nlm.nih.gov/pubmed/29721024

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