Study of the Role of siRNA Mediated Promoter Methylation in DNMT3B Knockdown and Alteration of Promoter Methylation of CDH1, GSTP1 Genes in MDA-MB -453 Cell Line

Promoter methylation is one of the main epigenetic mechanisms that leads to the inactivation of tumor suppressor genes during carcinogenesis. Due to the reversible nature of DNA methylation, many studies have been performed to correct theses epigenetic defects by inhibiting DNA methyltransferases (D...

Descripción completa

Detalles Bibliográficos
Autores principales: Naghitorabi, Mojgan, Mir Mohammad Sadeghi, Hamid, Mohammadi Asl, Javad, Rabbani, Mohammad, Jafarian-Dehkordi, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603887/
https://www.ncbi.nlm.nih.gov/pubmed/28979331

Ejemplares similares

Ejemplares similares