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A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells
Iron (Fe) species play a number of biologically and pathologically important roles. In particular, iron is a key element in oxygen sensing in living tissue where its metabolism is intimately linked with oxygen metabolism. Regulation of redox balance of labile iron species to prevent the generation o...
Autores principales: | Hirayama, Tasuku, Tsuboi, Hitomi, Niwa, Masato, Miki, Ayaji, Kadota, Satoki, Ikeshita, Yukie, Okuda, Kensuke, Nagasawa, Hideko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603896/ https://www.ncbi.nlm.nih.gov/pubmed/28959409 http://dx.doi.org/10.1039/c6sc05457a |
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