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Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles
[Image: see text] An alternative approach toward the simple and robust synthesis of highly substituted peptidic thiazole derivatives using Ugi-multicomponent reaction (U-MCR) is described. Thus, we introduced the enantiopure (R)-2-methyl-2-isocyano-3-(tritylthio)propanoate as a novel class of isocya...
Autores principales: | Vishwanatha, Thimmalapura M., Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603900/ https://www.ncbi.nlm.nih.gov/pubmed/28817272 http://dx.doi.org/10.1021/acs.joc.7b01615 |
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