Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

Monoclonal antibodies find broad application as therapy for various types of cancer by employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated functions of antibodies that engage immune effector cells, such as NK cells, represents a strategy to influence effector cell ac...

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Detalles Bibliográficos
Autores principales: Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604060/
https://www.ncbi.nlm.nih.gov/pubmed/28959256
http://dx.doi.org/10.3389/fimmu.2017.01112

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