The Responses of Mouse Preimplantation Embryos to Leptin In Vitro in a Transgenerational Model for Obesity

The aim of the present study was to test the hypothesis that leptin can directly mediate the negative effect of maternal obesity on preimplantation embryos. As previously shown, maternal obesity retards early embryonic development in vivo and increases the incidence of apoptosis in blastocysts. When...

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Detalles Bibliográficos
Autores principales: Kšiňanová, Martina, Čikoš, Štefan, Babel’ová, Janka, Šefčíková, Zuzana, Špirková, Alexandra, Koppel, Juraj, Fabian, Dušan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604062/
https://www.ncbi.nlm.nih.gov/pubmed/28959235
http://dx.doi.org/10.3389/fendo.2017.00233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604062/
https://www.ncbi.nlm.nih.gov/pubmed/28959235
http://dx.doi.org/10.3389/fendo.2017.00233

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