Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies against nuclear components. Lupus nephritis (LN) is the major cause of morbidity and mortality in patients with SLE. Central to the pathogenesis of SLE is the accumulation of cellul...

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Detalles Bibliográficos
Autores principales: Rother, Nils, Pieterse, Elmar, Lubbers, Jelle, Hilbrands, Luuk, van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604071/
https://www.ncbi.nlm.nih.gov/pubmed/28959262
http://dx.doi.org/10.3389/fimmu.2017.01136

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