Cargando…
Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment
A detailed understanding of the molecular pathways and cellular interactions that result in islet beta cell (β cell) destruction is essential for the development and implementation of effective therapies for prevention or reversal of type 1 diabetes (T1D). However, events that define the pathogenesi...
Autores principales: | Newby, Brittney N., Mathews, Clayton E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604085/ https://www.ncbi.nlm.nih.gov/pubmed/28959234 http://dx.doi.org/10.3389/fendo.2017.00232 |
Ejemplares similares
-
The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes
por: Russell, Mark A., et al.
Publicado: (2023) -
The Foundation for Engineering a Pancreatic Islet Niche
por: Patel, Smit N., et al.
Publicado: (2022) -
Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors
por: Landry, Laurie G., et al.
Publicado: (2021) -
Unlocking the post-transplant microenvironment for successful islet function and survival
por: Doherty, Daniel T., et al.
Publicado: (2023) -
Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study
por: Krogvold, Lars, et al.
Publicado: (2022)