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Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012

BACKGROUND: Pyogenic liver abscesses (PLA) are increasingly managed by percutaneous treatment instead of surgery, but there are limited data about postdischarge outcomes. Postdischarge services and factors predicting poor outcomes have not been described. METHODS: We performed a retrospective, descr...

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Autores principales: Gallagher, Megan C, Andrews, Mary-Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604130/
https://www.ncbi.nlm.nih.gov/pubmed/28948182
http://dx.doi.org/10.1093/ofid/ofx159
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author Gallagher, Megan C
Andrews, Mary-Margaret
author_facet Gallagher, Megan C
Andrews, Mary-Margaret
author_sort Gallagher, Megan C
collection PubMed
description BACKGROUND: Pyogenic liver abscesses (PLA) are increasingly managed by percutaneous treatment instead of surgery, but there are limited data about postdischarge outcomes. Postdischarge services and factors predicting poor outcomes have not been described. METHODS: We performed a retrospective, descriptive case series at a single center assessing treatment and outpatient follow-up for patients treated for PLA from 2007 to 2012. We reviewed the electronic medical record for patient characteristics and outcomes. Data for care received at other facilities were not available. In our analysis, we compared patients with malignancy with those without and attempted to determine predictors of emergency department (ED) visits and hospital readmissions. RESULTS: Of 125 patients identified with PLA, 12 had surgical drainage, 23 had percutaneous aspiration, 78 had percutaneous drainage (PD), 11 had no drainage, and 1 was made comfort measures only. Seventy (60%) were discharged with a drain, and 31 (25%) were discharged on intravenous (IV) antibiotics. After discharge, 46 (38%) had ED visits and 36 (30%) were readmitted within 30 days of discharge. Fourteen (12%) had complications from antibiotics, and 4 (13%) had complications from peripherally inserted center catheter lines. A total of 8 patients, 5 in-hospital and 3 postdischarge, died. In our analysis of risk factors for 90-day postdischarge ED visit/readmission, only malignancy was a predictor. CONCLUSIONS: Pyogenic liver abscess patients have intense postdischarge needs (drain management, IV antibiotics) and a high rate of ED visits and readmissions. Although PD provides source control without surgery, ambulatory needs are now more complex, requiring multidisciplinary collaboration.
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spelling pubmed-56041302017-09-25 Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012 Gallagher, Megan C Andrews, Mary-Margaret Open Forum Infect Dis Major Article BACKGROUND: Pyogenic liver abscesses (PLA) are increasingly managed by percutaneous treatment instead of surgery, but there are limited data about postdischarge outcomes. Postdischarge services and factors predicting poor outcomes have not been described. METHODS: We performed a retrospective, descriptive case series at a single center assessing treatment and outpatient follow-up for patients treated for PLA from 2007 to 2012. We reviewed the electronic medical record for patient characteristics and outcomes. Data for care received at other facilities were not available. In our analysis, we compared patients with malignancy with those without and attempted to determine predictors of emergency department (ED) visits and hospital readmissions. RESULTS: Of 125 patients identified with PLA, 12 had surgical drainage, 23 had percutaneous aspiration, 78 had percutaneous drainage (PD), 11 had no drainage, and 1 was made comfort measures only. Seventy (60%) were discharged with a drain, and 31 (25%) were discharged on intravenous (IV) antibiotics. After discharge, 46 (38%) had ED visits and 36 (30%) were readmitted within 30 days of discharge. Fourteen (12%) had complications from antibiotics, and 4 (13%) had complications from peripherally inserted center catheter lines. A total of 8 patients, 5 in-hospital and 3 postdischarge, died. In our analysis of risk factors for 90-day postdischarge ED visit/readmission, only malignancy was a predictor. CONCLUSIONS: Pyogenic liver abscess patients have intense postdischarge needs (drain management, IV antibiotics) and a high rate of ED visits and readmissions. Although PD provides source control without surgery, ambulatory needs are now more complex, requiring multidisciplinary collaboration. Oxford University Press 2017-07-27 /pmc/articles/PMC5604130/ /pubmed/28948182 http://dx.doi.org/10.1093/ofid/ofx159 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Article
Gallagher, Megan C
Andrews, Mary-Margaret
Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title_full Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title_fullStr Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title_full_unstemmed Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title_short Postdischarge Outcomes of Pyogenic Liver Abscesses: Single-Center Experience 2007–2012
title_sort postdischarge outcomes of pyogenic liver abscesses: single-center experience 2007–2012
topic Major Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604130/
https://www.ncbi.nlm.nih.gov/pubmed/28948182
http://dx.doi.org/10.1093/ofid/ofx159
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