Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection

Current hepatitis C virus (HCV) treatment guidelines recommend treating HCV/human immunodeficiency virus (HIV)-coinfected individuals similar to HCV-monoinfected individuals. Recently inferior response rates to direct acting antiviral (DAA) therapy in HCV/HIV coinfection have been reported. Our Germ...

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Autores principales: Boesecke, Christoph, Ingiliz, Patrick, Berger, Florian, Lutz, Thomas, Schewe, Knud, Schulze zur Wiesch, Julian, Baumgarten, Axel, Christensen, Stefan, Rockstroh, Jürgen K, Mauss, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604144/
https://www.ncbi.nlm.nih.gov/pubmed/28948181
http://dx.doi.org/10.1093/ofid/ofx158
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author Boesecke, Christoph
Ingiliz, Patrick
Berger, Florian
Lutz, Thomas
Schewe, Knud
Schulze zur Wiesch, Julian
Baumgarten, Axel
Christensen, Stefan
Rockstroh, Jürgen K
Mauss, Stefan
author_facet Boesecke, Christoph
Ingiliz, Patrick
Berger, Florian
Lutz, Thomas
Schewe, Knud
Schulze zur Wiesch, Julian
Baumgarten, Axel
Christensen, Stefan
Rockstroh, Jürgen K
Mauss, Stefan
author_sort Boesecke, Christoph
collection PubMed
description Current hepatitis C virus (HCV) treatment guidelines recommend treating HCV/human immunodeficiency virus (HIV)-coinfected individuals similar to HCV-monoinfected individuals. Recently inferior response rates to direct acting antiviral (DAA) therapy in HCV/HIV coinfection have been reported. Our German hepatitis C cohort (GECCO) cohort data show that coinfected patients with liver cirrhosis are less likely to achieve viral eradication.
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spelling pubmed-56041442017-09-25 Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection Boesecke, Christoph Ingiliz, Patrick Berger, Florian Lutz, Thomas Schewe, Knud Schulze zur Wiesch, Julian Baumgarten, Axel Christensen, Stefan Rockstroh, Jürgen K Mauss, Stefan Open Forum Infect Dis Brief Report Current hepatitis C virus (HCV) treatment guidelines recommend treating HCV/human immunodeficiency virus (HIV)-coinfected individuals similar to HCV-monoinfected individuals. Recently inferior response rates to direct acting antiviral (DAA) therapy in HCV/HIV coinfection have been reported. Our German hepatitis C cohort (GECCO) cohort data show that coinfected patients with liver cirrhosis are less likely to achieve viral eradication. Oxford University Press 2017-07-27 /pmc/articles/PMC5604144/ /pubmed/28948181 http://dx.doi.org/10.1093/ofid/ofx158 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Boesecke, Christoph
Ingiliz, Patrick
Berger, Florian
Lutz, Thomas
Schewe, Knud
Schulze zur Wiesch, Julian
Baumgarten, Axel
Christensen, Stefan
Rockstroh, Jürgen K
Mauss, Stefan
Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title_full Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title_fullStr Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title_full_unstemmed Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title_short Liver Cirrhosis as a Risk Factor for Direct-Acting Antiviral Therapy Failure in Real-Life Hepatitis C Virus/Human Immunodeficiency Virus Coinfection
title_sort liver cirrhosis as a risk factor for direct-acting antiviral therapy failure in real-life hepatitis c virus/human immunodeficiency virus coinfection
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604144/
https://www.ncbi.nlm.nih.gov/pubmed/28948181
http://dx.doi.org/10.1093/ofid/ofx158
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