HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins

Background and Aim: Hairy enhancer of split-1 (HES1) is a downstream transcriptional factor of Notch signaling pathway, which was found to be related to chemoresistance. This study was aimed to investigate the role of HES1 in chemoresistance of colorectal cancer (CRC). Methods: Tissue microarray was...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Ke, Jia, He, Zhen, Chen, Zexian, Huang, Qinghua, Ai, Wenjia, Wang, Guoqiang, Wei, Yisheng, Zou, Xiangcai, Zhang, Shi, Lan, Ping, Hong, Chuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604212/
https://www.ncbi.nlm.nih.gov/pubmed/28928869
http://dx.doi.org/10.7150/jca.19142

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