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Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling
BACKGROUND: Meningiomas are the most common primary intracranial tumors in adults. While a majority of meningiomas are slow growing neoplasms that may cured by surgical resection, a subset demonstrates more aggressive behavior and insidiously recurs despite surgery and radiation, without effective a...
Autores principales: | Mei, Yu, Du, Ziming, Hu, Changchen, Greenwald, Noah F., Abedalthagafi, Malak, Agar, Nathalie Y.R., Dunn, Gavin P., Bi, Wenya Linda, Santagata, Sandro, Dunn, Ian F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604305/ https://www.ncbi.nlm.nih.gov/pubmed/28923059 http://dx.doi.org/10.1186/s12964-017-0189-7 |
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