Inflammasome lights up in systemic sclerosis

Systemic sclerosis (SSc) is a pro-fibrotic condition with a poorly understood aetiology. Evidence presented by Artlett et al. in this issue suggests that the microRNA miR-155 is key, with its involvement dependent on the NLRP3 inflammasome. This links epigenetic events with inflammasome signalling i...

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Detalles Bibliográficos
Autores principales: Henderson, John, O’Reilly, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604346/
https://www.ncbi.nlm.nih.gov/pubmed/28923085
http://dx.doi.org/10.1186/s13075-017-1420-z
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author Henderson, John
O’Reilly, Steven
author_facet Henderson, John
O’Reilly, Steven
author_sort Henderson, John
collection PubMed
description Systemic sclerosis (SSc) is a pro-fibrotic condition with a poorly understood aetiology. Evidence presented by Artlett et al. in this issue suggests that the microRNA miR-155 is key, with its involvement dependent on the NLRP3 inflammasome. This links epigenetic events with inflammasome signalling in SSc and opens the door to new therapeutic strategies for the treatment of SSc.
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spelling pubmed-56043462017-09-21 Inflammasome lights up in systemic sclerosis Henderson, John O’Reilly, Steven Arthritis Res Ther Editorial Systemic sclerosis (SSc) is a pro-fibrotic condition with a poorly understood aetiology. Evidence presented by Artlett et al. in this issue suggests that the microRNA miR-155 is key, with its involvement dependent on the NLRP3 inflammasome. This links epigenetic events with inflammasome signalling in SSc and opens the door to new therapeutic strategies for the treatment of SSc. BioMed Central 2017-09-18 2017 /pmc/articles/PMC5604346/ /pubmed/28923085 http://dx.doi.org/10.1186/s13075-017-1420-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Editorial
Henderson, John
O’Reilly, Steven
Inflammasome lights up in systemic sclerosis
title Inflammasome lights up in systemic sclerosis
title_full Inflammasome lights up in systemic sclerosis
title_fullStr Inflammasome lights up in systemic sclerosis
title_full_unstemmed Inflammasome lights up in systemic sclerosis
title_short Inflammasome lights up in systemic sclerosis
title_sort inflammasome lights up in systemic sclerosis
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604346/
https://www.ncbi.nlm.nih.gov/pubmed/28923085
http://dx.doi.org/10.1186/s13075-017-1420-z
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