Cargando…

Hyperpolarized (13)C Diffusion MRS of Co-Polarized Pyruvate and Fumarate to Measure Lactate Export and Necrosis

Background: Non-invasive tumor characterization and monitoring are among the key goals of medical imaging. Using hyperpolarized (13)C-labelled metabolic probes fast metabolic pathways can be probed in real-time, providing new opportunities for tumor characterization. In this in vitro study, we inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feuerecker, Benedikt, Durst, Markus, Michalik, Michael, Schneider, Günter, Saur, Dieter, Menzel, Marion, Schwaiger, Markus, Schilling, Franz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604459/ https://www.ncbi.nlm.nih.gov/pubmed/28928899 http://dx.doi.org/10.7150/jca.20250

Ejemplares similares

Assessment of (213)Bi-anti-EGFR MAb treatment efficacy in malignant cancer cells with [1-(13)C]pyruvate and [(18)F]FDG
por: Feuerecker, Benedikt, et al.
Publicado: (2019)

Imaging of pH in vivo using hyperpolarized (13)C-labelled zymonic acid
por: Düwel, Stephan, et al.
Publicado: (2017)

Hyperpolarized Amino Acid Derivatives as Multivalent Magnetic Resonance pH Sensor Molecules
por: Hundshammer, Christian, et al.
Publicado: (2018)

Dynamic Imaging of Glucose and Lactate Metabolism by (13)C-MRS without Hyperpolarization
por: Brender, Jeffrey R., et al.
Publicado: (2019)

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
por: Timm, Kerstin N., et al.
Publicado: (2018)

Pyruvate‐lactate exchange and glucose uptake in human prostate cancer cell models. A study in xenografts and suspensions by hyperpolarized [1‐(13)C]pyruvate MRS and [(18)F]FDG‐PET
por: van Heijster, Frits H.A., et al.
Publicado: (2020)

In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized (13)C-Pyruvate
por: Hu, Simon, et al.
Publicado: (2009)

Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

A comparison of quantitative methods for clinical imaging with hyperpolarized (13)C‐pyruvate
por: Daniels, Charlie J., et al.
Publicado: (2016)

Imaging Hyperpolarized Pyruvate and Lactate after Blood–Brain Barrier Disruption with Focused Ultrasound
por: Peeters, Tom H., et al.
Publicado: (2019)

Lactate saturation limits bicarbonate detection in hyperpolarized (13)C‐pyruvate MRI of the brain
por: Bøgh, Nikolaj, et al.
Publicado: (2022)

Author Correction: Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Fast Padé Transform Accelerated CSI for Hyperpolarized MRS
por: Hansen, Esben Szocska Søvsø, et al.
Publicado: (2016)

Simultaneous characterization of tumor cellularity and the Warburg effect with PET, MRI and hyperpolarized (13)C-MRSI
por: Hundshammer, Christian, et al.
Publicado: (2018)

Synthesis of (13)C and (2)H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate
por: Brahms, Arne, et al.
Publicado: (2022)

Hyperpolarized [1,4-(13)C(2)]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis
por: Miller, Jack J., et al.
Publicado: (2018)

Rapid hyperpolarization and purification of the metabolite fumarate in aqueous solution
por: Knecht, Stephan, et al.
Publicado: (2021)

Non-Invasive Differentiation of M1 and M2 Activation in Macrophages Using Hyperpolarized (13)C MRS of Pyruvate and DHA at 1.47 Tesla
por: Qiao, Kai, et al.
Publicado: (2021)

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse
por: Marco-Rius, Irene, et al.
Publicado: (2013)

Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized (13)C Pyruvate MRI
por: Sriram, Renuka, et al.
Publicado: (2018)

Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies
por: Larson, Peder EZ, et al.
Publicado: (2023)

LIGHT-SABRE Hyperpolarizes 1-(13)C-Pyruvate Continuously without Magnetic Field Cycling
por: Pravdivtsev, Andrey N., et al.
Publicado: (2023)

Metabolic Response of Pancreatic Carcinoma Cells under Treatment with Dichloroacetate
por: Feuerecker, Benedikt, et al.
Publicado: (2021)

Conversion of Hyperpolarized [1-(13)C]Pyruvate in Breast Cancer Cells Depends on Their Malignancy, Metabolic Program and Nutrient Microenvironment
por: Grashei, Martin, et al.
Publicado: (2022)

Pyruvate Carboxylation in Different Model Systems Studied by (13)C MRS
por: Sonnewald, Ursula, et al.
Publicado: (2010)

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS
por: Le Page, Lydia M., et al.
Publicado: (2016)

Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-(13)C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of Principle Study
por: Zaccagna, Fulvio, et al.
Publicado: (2022)

Metabolic alterations in acute myocardial ischemia-reperfusion injury and necrosis using in vivo hyperpolarized [1-(13)C] pyruvate MR spectroscopy
por: Moon, Chung-Man, et al.
Publicado: (2019)

A referenceless Nyquist ghost correction workflow for echo planar imaging of hyperpolarized [1‐(13)C]pyruvate and [1‐(13)C]lactate
por: Wang, Jiazheng, et al.
Publicado: (2017)

Comparison of (13)C MRI of hyperpolarized [1‐(13)C]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model
por: Fala, Maria, et al.
Publicado: (2021)

Hyperpolarized [1-(13)C]pyruvate Magnetic Resonance Spectroscopy Shows That Agmatine Increased Lactate Production in the Brain of Type 2 Diabetic Mice
por: Choi, Young-Suk, et al.
Publicado: (2023)

Diverse metabolic response of cancer cells treated with a (213)Bi-anti-EGFR-immunoconjugate
por: Feuerecker, Benedikt, et al.
Publicado: (2021)

Reduced Warburg Effect in Cancer Cells Undergoing Autophagy: Steady- State (1)H-MRS and Real-Time Hyperpolarized (13)C-MRS Studies
por: Lin, Gigin, et al.
Publicado: (2014)

Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate
por: Serrao, Eva M., et al.
Publicado: (2016)

Molecular detection of inflammation in cell models using hyperpolarized (13)C-pyruvate
por: Sriram, Renuka, et al.
Publicado: (2018)

Comparison between volume and surface coils for pig cardiac metabolism studies with hyperpolarized 13C MRS
por: Giovannetti, Giulio, et al.
Publicado: (2011)

A Catalyzing Phantom for Reproducible Dynamic Conversion of Hyperpolarized [1-(13)C]-Pyruvate
por: Walker, Christopher M., et al.
Publicado: (2013)

Metabolism of hyperpolarized [1‐(13)C]pyruvate through alternate pathways in rat liver
por: Jin, Eunsook S., et al.
Publicado: (2016)

Effects of fasting on serial measurements of hyperpolarized [1‐(13)C]pyruvate metabolism in tumors
por: Serrao, Eva M., et al.
Publicado: (2016)

Hyperpolarized [1‐(13)C] pyruvate as a possible diagnostic tool in liver disease
por: Kjærgaard, Uffe, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_c71sgd4m2l8j968blim357nllr