Cargando…

Modelling the free energy profile of the mitochondrial ADP/ATP carrier

The mitochondrial ADP/ATP carrier catalyses the equimolar exchange of adenosine di- and tri-phosphates. It operates by an alternating access mechanism in which a single substrate-binding site is made available either to the mitochondrial matrix or the intermembrane space through conformational chang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Springett, Roger, King, Martin S., Crichton, Paul G., Kunji, Edmund R.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Pub. Co 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604490/ https://www.ncbi.nlm.nih.gov/pubmed/28554566 http://dx.doi.org/10.1016/j.bbabio.2017.05.006

Ejemplares similares

Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier
por: King, Martin S., et al.
Publicado: (2016)

Corrigendum to “Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier” [Biochim. Biophys. Acta 1857 (2016) 14–22]
por: King, Martin S., et al.
Publicado: (2016)

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier
por: Ruprecht, Jonathan J., et al.
Publicado: (2019)

Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism
por: Cimadamore‐Werthein, Camila, et al.
Publicado: (2023)

Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier
por: Ruprecht, Jonathan J, et al.
Publicado: (2019)

The mitochondrial ADP/ATP carrier exists and functions as a monomer
por: Kunji, Edmund R.S., et al.
Publicado: (2020)

Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity
por: Dehez, François, et al.
Publicado: (2017)

Characterization of drug-induced human mitochondrial ADP/ATP carrier inhibition
por: Jaiquel Baron, Stephany, et al.
Publicado: (2021)

Cardiolipin dynamics and binding to conserved residues in the mitochondrial ADP/ATP carrier
por: Duncan, Anna L., et al.
Publicado: (2018)

Calcium‐regulated mitochondrial ATP‐Mg/P(i) carriers evolved from a fusion of an EF‐hand regulatory domain with a mitochondrial ADP/ATP carrier‐like domain
por: Harborne, Steven P. D., et al.
Publicado: (2018)

Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle
por: Mavridou, Vasiliki, et al.
Publicado: (2022)

Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism
por: Harborne, Steven P. D., et al.
Publicado: (2017)

The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism
por: Crichton, Paul G., et al.
Publicado: (2017)

Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier
por: Harborne, Steven P.D., et al.
Publicado: (2015)

A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Cryptosporidium parvum Confers a Broad Nucleotide Specificity
por: King, Martin S., et al.
Publicado: (2020)

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
por: Kunji, Edmund R.S., et al.
Publicado: (2020)

The SLC25 Mitochondrial Carrier Family: Structure and Mechanism
por: Ruprecht, Jonathan J., et al.
Publicado: (2020)

The free-living flagellate Paratrimastix pyriformis uses a distinct mitochondrial carrier to balance adenine nucleotide pools
por: Zítek, Justyna, et al.
Publicado: (2023)

H(+) Transport is an Integral Function of the Mitochondrial ADP/ATP Carrier
por: Bertholet, Ambre M., et al.
Publicado: (2019)

Trends in Thermostability Provide Information on the Nature of Substrate, Inhibitor, and Lipid Interactions with Mitochondrial Carriers
por: Crichton, Paul G., et al.
Publicado: (2015)

Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier
por: Yao, Shihao, et al.
Publicado: (2022)

Mitochondrial ADP/ATP Carrier 1 Is Important for the Growth of Toxoplasma Tachyzoites
por: Qian, Jiahui, et al.
Publicado: (2023)

Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency
por: Tavoulari, Sotiria, et al.
Publicado: (2022)

The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione
por: Booty, Lee M., et al.
Publicado: (2015)

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane
por: Claypool, Steven M., et al.
Publicado: (2008)

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane
por: Claypool, Steven M., et al.
Publicado: (2012)

Lipid, Detergent, and Coomassie Blue G-250 Affect the Migration of Small Membrane Proteins in Blue Native Gels: MITOCHONDRIAL CARRIERS MIGRATE AS MONOMERS NOT DIMERS
por: Crichton, Paul G., et al.
Publicado: (2013)

Cardiolipin, conformation, and respiratory complex-dependent oligomerization of the major mitochondrial ADP/ATP carrier in yeast
por: Senoo, N., et al.
Publicado: (2020)

The effects of cardiolipin on the structural dynamics of the mitochondrial ADP/ATP carrier in its cytosol-open state
por: Yi, Qiuzi, et al.
Publicado: (2022)

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
por: Tavoulari, Sotiria, et al.
Publicado: (2022)

The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state
por: Tavoulari, Sotiria, et al.
Publicado: (2019)

Investigating the Broad Matrix-Gate Network in the Mitochondrial ADP/ATP Carrier through Molecular Dynamics Simulations
por: Yao, Shihao, et al.
Publicado: (2022)

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel
Publicado: (1990)

Function-Related Asymmetry of the Interactions between Matrix Loops and Conserved Sequence Motifs in the Mitochondrial ADP/ATP Carrier
por: Yi, Qiuzi, et al.
Publicado: (2022)

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant
por: Senoo, Nanami, et al.
Publicado: (2023)

Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases
por: Fu, Jiaqi, et al.
Publicado: (2022)

Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease
por: Boczonadi, Veronika, et al.
Publicado: (2018)

Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
por: Thangaratnarajah, Chancievan, et al.
Publicado: (2014)

Thermodynamic efficiency, reversibility, and degree of coupling in energy conservation by the mitochondrial respiratory chain
por: Wikström, Mårten, et al.
Publicado: (2020)

Exome sequencing identifies a disease variant of the mitochondrial ATP‐Mg/Pi carrier SLC25A25 in two families with kidney stones
por: Jabalameli, M. Reza, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o8vhb1mv3rfskd94hf5121chhi