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Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma

BACKGROUND: Adoptive natural killer (NK) cell transfer is being increasingly used as cancer treatment. However, clinical responses have so far been limited to patients with hematological malignancies. A potential limiting factor in patients with solid tumors is defective homing of the infused NK cel...

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Detalles Bibliográficos
Autores principales: Kremer, Veronika, Ligtenberg, Maarten, Zendehdel, Rosa, Seitz, Christina, Duivenvoorden, Annet, Wennerberg, Erik, Colón, Eugenia, Scherman-Plogell, Ann-Helén, Lundqvist, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604543/
https://www.ncbi.nlm.nih.gov/pubmed/28923105
http://dx.doi.org/10.1186/s40425-017-0275-9

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