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A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis
DNA double-strand breaks (DSBs) are a hazardous form of damage that can potentially cause cell death or genomic rearrangements. In mammalian G1- and G2-phase cells, DSBs are repaired with two-component kinetics. In both phases, a fast process uses canonical nonhomologous end joining (c-NHEJ) to repa...
Autores principales: | Löbrich, Markus, Jeggo, Penny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Trends Journals
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604544/ https://www.ncbi.nlm.nih.gov/pubmed/28739276 http://dx.doi.org/10.1016/j.tibs.2017.06.011 |
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