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Polygonatum odoratum lectin promotes BECN1 expression and induces autophagy in malignant melanoma by regulation of miR1290

Autophagy is not only a survival response to growth-factor or nutrient deprivation but also an important mechanism for tumor-cell suicide, including melanoma. Polygonatum odoratum lectin (POL) displays apoptosis- and autophagy-inducing effects in many human tumors. POL also inhibits the growth of me...

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Detalles Bibliográficos
Autores principales: Luan, Wenkang, Qian, Yao, Ni, Xin, Chanda, Tonmoy Kumar, Xia, Yun, Wang, Jinlong, Yan, Yulan, Xu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604572/
https://www.ncbi.nlm.nih.gov/pubmed/29066911
http://dx.doi.org/10.2147/OTT.S147406

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