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Polygonatum odoratum lectin promotes BECN1 expression and induces autophagy in malignant melanoma by regulation of miR1290
Autophagy is not only a survival response to growth-factor or nutrient deprivation but also an important mechanism for tumor-cell suicide, including melanoma. Polygonatum odoratum lectin (POL) displays apoptosis- and autophagy-inducing effects in many human tumors. POL also inhibits the growth of me...
Autores principales: | Luan, Wenkang, Qian, Yao, Ni, Xin, Chanda, Tonmoy Kumar, Xia, Yun, Wang, Jinlong, Yan, Yulan, Xu, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604572/ https://www.ncbi.nlm.nih.gov/pubmed/29066911 http://dx.doi.org/10.2147/OTT.S147406 |
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