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Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts

The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity o...

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Autores principales: Yates, Max, Watts, Richard, Bajema, Ingeborg, Cid, Maria, Crestani, Bruno, Hauser, Thomas, Hellmich, Bernhard, Holle, Julia, Laudien, Martin, Little, Mark A, Luqmani, Raashid Ahmed, Mahr, Alfred, Merkel, Peter, Mills, John, Mooney, Janice, Segelmark, Mårten, Tesar, Vladimir, Westman, Kerstin W A, Vaglio, Augusto, Yalçındağ, Nilüfer, Jayne, David R, Mukhtyar, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604609/
https://www.ncbi.nlm.nih.gov/pubmed/28955487
http://dx.doi.org/10.1136/rmdopen-2017-000449
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author Yates, Max
Watts, Richard
Bajema, Ingeborg
Cid, Maria
Crestani, Bruno
Hauser, Thomas
Hellmich, Bernhard
Holle, Julia
Laudien, Martin
Little, Mark A
Luqmani, Raashid Ahmed
Mahr, Alfred
Merkel, Peter
Mills, John
Mooney, Janice
Segelmark, Mårten
Tesar, Vladimir
Westman, Kerstin W A
Vaglio, Augusto
Yalçındağ, Nilüfer
Jayne, David R
Mukhtyar, Chetan
author_facet Yates, Max
Watts, Richard
Bajema, Ingeborg
Cid, Maria
Crestani, Bruno
Hauser, Thomas
Hellmich, Bernhard
Holle, Julia
Laudien, Martin
Little, Mark A
Luqmani, Raashid Ahmed
Mahr, Alfred
Merkel, Peter
Mills, John
Mooney, Janice
Segelmark, Mårten
Tesar, Vladimir
Westman, Kerstin W A
Vaglio, Augusto
Yalçındağ, Nilüfer
Jayne, David R
Mukhtyar, Chetan
author_sort Yates, Max
collection PubMed
description The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity of the recommendations among people who self-identify as clinicians caring for patients with vasculitis. In addition to the task force, a learned society (European Vasculitis Society—EUVAS) was invited, through online survey, to rate independently the strength of evidence of each recommendation to obtain an indication of the agreement among the final target audience and ultimate end-users of the recommendations. The survey took place in June 2015. Of the 158 EUVAS members surveyed, there were 88 responses (55.7%). There was a large degree of agreement in the voting patterns between EUVAS survey participants and task force members. Notable exceptions were lower grades for the recommendation of the use of rituximab for remission induction in patients with eosinophilic granulomatosis with polyangiitis and for methotrexate and mycophenolate mofetil as remission maintenance agents in patients with granulomatosis with polyangiitis/microscopic polyangiitis by EUVAS members. These results are encouraging and suggest that the voting patterns of the task force are representative of the wider vasculitis community. We recommend future recommendations adopt this approach for data/expert-based treatment guidelines, especially for multisystem diseases.
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spelling pubmed-56046092017-09-27 Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts Yates, Max Watts, Richard Bajema, Ingeborg Cid, Maria Crestani, Bruno Hauser, Thomas Hellmich, Bernhard Holle, Julia Laudien, Martin Little, Mark A Luqmani, Raashid Ahmed Mahr, Alfred Merkel, Peter Mills, John Mooney, Janice Segelmark, Mårten Tesar, Vladimir Westman, Kerstin W A Vaglio, Augusto Yalçındağ, Nilüfer Jayne, David R Mukhtyar, Chetan RMD Open Vasculitis The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity of the recommendations among people who self-identify as clinicians caring for patients with vasculitis. In addition to the task force, a learned society (European Vasculitis Society—EUVAS) was invited, through online survey, to rate independently the strength of evidence of each recommendation to obtain an indication of the agreement among the final target audience and ultimate end-users of the recommendations. The survey took place in June 2015. Of the 158 EUVAS members surveyed, there were 88 responses (55.7%). There was a large degree of agreement in the voting patterns between EUVAS survey participants and task force members. Notable exceptions were lower grades for the recommendation of the use of rituximab for remission induction in patients with eosinophilic granulomatosis with polyangiitis and for methotrexate and mycophenolate mofetil as remission maintenance agents in patients with granulomatosis with polyangiitis/microscopic polyangiitis by EUVAS members. These results are encouraging and suggest that the voting patterns of the task force are representative of the wider vasculitis community. We recommend future recommendations adopt this approach for data/expert-based treatment guidelines, especially for multisystem diseases. BMJ Publishing Group 2017-06-15 /pmc/articles/PMC5604609/ /pubmed/28955487 http://dx.doi.org/10.1136/rmdopen-2017-000449 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Vasculitis
Yates, Max
Watts, Richard
Bajema, Ingeborg
Cid, Maria
Crestani, Bruno
Hauser, Thomas
Hellmich, Bernhard
Holle, Julia
Laudien, Martin
Little, Mark A
Luqmani, Raashid Ahmed
Mahr, Alfred
Merkel, Peter
Mills, John
Mooney, Janice
Segelmark, Mårten
Tesar, Vladimir
Westman, Kerstin W A
Vaglio, Augusto
Yalçındağ, Nilüfer
Jayne, David R
Mukhtyar, Chetan
Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title_full Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title_fullStr Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title_full_unstemmed Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title_short Validation of the EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis by disease content experts
title_sort validation of the eular/era-edta recommendations for the management of anca-associated vasculitis by disease content experts
topic Vasculitis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604609/
https://www.ncbi.nlm.nih.gov/pubmed/28955487
http://dx.doi.org/10.1136/rmdopen-2017-000449
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