Cargando…

Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretion

OBJECTIVE: Tumour necrosis factor alpha (TNF-α) plays an important role in rheumatoid arthritis (RA). TNF-α is synthesised as a membrane-anchored precursor and is fully activated by a disintegrin and metalloproteinase 17 (ADAM17)-mediated ectodomain shedding. Nardilysin (NRDC) facilitates ectodomain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujii, Takayuki, Nishi, Eiichiro, Ito, Hiromu, Yoshitomi, Hiroyuki, Furu, Moritoshi, Okabe, Namiko, Ohno, Mikiko, Nishi, Kiyoto, Morita, Yusuke, Morita, Yugo, Azukizawa, Masayuki, Okahata, Akinori, Tomizawa, Takuya, Kimura, Takeshi, Matsuda, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RMD Open 2017
Materias:	Animal Models
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604610/ https://www.ncbi.nlm.nih.gov/pubmed/28955486 http://dx.doi.org/10.1136/rmdopen-2017-000436

Ejemplares similares

Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression
por: Morita, Yusuke, et al.
Publicado: (2017)

Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis
por: Saijo, Sayaka, et al.
Publicado: (2022)

Critical roles of nardilysin in the maintenance of body temperature homoeostasis
por: Hiraoka, Yoshinori, et al.
Publicado: (2014)

Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 3
por: Kasai, Yosuke, et al.
Publicado: (2017)

Factors affecting walking ability in female patients with rheumatoid arthritis
por: Morita, Yugo, et al.
Publicado: (2018)

Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach
por: Kimura, Yuto, et al.
Publicado: (2017)

Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes
por: Ishizu-Higashi, Shoko, et al.
Publicado: (2014)

IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis
por: Yahagi, Ayano, et al.
Publicado: (2019)

Correlation in the Coronal Angle between Knee and Hindfoot Was Observed in Patients with Rheumatoid Arthritis Unless Talocrural Joint Was Destroyed
por: Nishitani, Kohei, et al.
Publicado: (2017)

Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α
por: Kanda, Keitaro, et al.
Publicado: (2012)

Serological and Progression Differences of Joint Destruction in the Wrist and the Feet in Rheumatoid Arthritis - A Cross-Sectional Cohort Study
por: Hamamoto, Yosuke, et al.
Publicado: (2015)

MCP/CCR2 Signaling Is Essential for Recruitment of Mesenchymal Progenitor Cells during the Early Phase of Fracture Healing
por: Ishikawa, Masahiro, et al.
Publicado: (2014)

TGF‐β induces the differentiation of human CXCL13‐producing CD4(+) T cells
por: Kobayashi, Shio, et al.
Publicado: (2015)

Low back pain precedes the development of new knee pain in the elderly population; a novel predictive score from a longitudinal cohort study
por: Ito, Hiromu, et al.
Publicado: (2019)

Ultrasonographic Changes of the Knee Joint Reflect Symptoms of Early Knee Osteoarthritis in General Population; The Nagahama Study
por: Saito, Motoo, et al.
Publicado: (2022)

Comprehensive microRNA Analysis Identifies miR-24 and miR-125a-5p as Plasma Biomarkers for Rheumatoid Arthritis
por: Murata, Koichi, et al.
Publicado: (2013)

Control of articular synovitis for bone and cartilage regeneration in rheumatoid arthritis
por: Ito, Hiromu, et al.
Publicado: (2018)

Absence of a Major Role for the Snai1 and Snai3 Genes in Regulating Skeletal Muscle Regeneration in Mice
por: Norton, Christine R., et al.
Publicado: (2013)

Stem Cell Antigen-1 in Skeletal Muscle Function
por: Bernstein, Harold S., et al.
Publicado: (2013)

The HDAC Inhibitor TSA Ameliorates a Zebrafish Model of Duchenne Muscular Dystrophy
por: Johnson, Nathan M., et al.
Publicado: (2013)

Significantly reduced lymphadenopathy, salivary gland infiltrates and proteinuria in MRL-lpr/lpr mice treated with ultrasoluble curcumin/turmeric: increased survival with curcumin treatment
por: Kurien, Biji T, et al.
Publicado: (2015)

The FVB Background Does Not Dramatically Alter the Dystrophic Phenotype of Mdx Mice
por: Wasala, Nalinda B., et al.
Publicado: (2015)

Suppression of arthritis-induced bone erosion by a CRAC channel antagonist
por: Blair, Harry C, et al.
Publicado: (2016)

Spontaneous destructive periodontitis and skeletal bone damage in transgenic mice carrying a human shared epitope-coding HLA-DRB1 allele
por: Gehlot, Prashasnika, et al.
Publicado: (2016)

Greater Colo-Rectal Activation Phenotype in Exercised mdx Mice
por: Nearing, Marie, et al.
Publicado: (2018)

Effect of celastrol on bone structure and mechanics in arthritic rats
por: Cascão, Rita, et al.
Publicado: (2017)

Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo
por: Guns, Laura-An, et al.
Publicado: (2017)

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance
por: Liu, Yudong, et al.
Publicado: (2018)

Exploratory Profiling of Urine MicroRNAs in the dy(2J)/dy(2J) Mouse Model of LAMA2-CMD: Relation to Disease Progression
por: Moreira Soares Oliveira, Bernardo, et al.
Publicado: (2018)

Bromodomain protein inhibition: a novel therapeutic strategy in rheumatic diseases
por: Klein, Kerstin
Publicado: (2018)

Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis
por: Schroeder, Juliane, et al.
Publicado: (2019)

Cardiac protection of germinated brown rice extract in rabbit model of chronic myocardial infarction
por: Petchdee, Soontaree, et al.
Publicado: (2020)

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice
por: Fortner, Karen A, et al.
Publicado: (2020)

Technical note: novel delivery methods for an enterotoxigenic Escherichia coli infection model in MUC4-locus sequenced weaner pigs()
por: Sterndale, Samantha O, et al.
Publicado: (2019)

Predicting ewe body condition score using adjusted liveweight for conceptus and fleece weight, height at withers, and previous body condition score record
por: Semakula, Jimmy, et al.
Publicado: (2021)

Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model
por: Fukuta, Masashi, et al.
Publicado: (2021)

A standardized model to study effects of varying 24-h colostrum dose on postnatal growth and development
por: Suárez-Trujillo, Aridany, et al.
Publicado: (2020)

Crossbreeding beef sires to dairy cows: cow, feedlot, and carcass performance
por: Foraker, Blake A, et al.
Publicado: (2022)

Systemic blockade of proBDNF inhibited the expansion and altered the transcriptomic expression in CD3(+)B220(+) cells in MRL/lpr lupus mice
por: Zha, An-Hui, et al.
Publicado: (2022)

Impact of age at first calving on performance traits in Irish beef herds
por: Twomey, Alan J, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5gctcave1rvn55gqtsectg3ss7