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Treatment efficacy and methotrexate-related toxicity in patients with rheumatoid arthritis receiving methotrexate in combination with adalimumab

BACKGROUND: Treatment of rheumatoid arthritis (RA) with a combination of methotrexate (MTX)+adalimumab (ADA) is more effective than ADA monotherapy. We assessed the toxicity of different doses of MTX and treatment efficacy of ADA+MTX in two trials. METHODS: Data originated from CONCERTO, in patients...

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Detalles Bibliográficos
Autores principales: Burmester, Gerd R, Kaeley, Gurjit S, Kavanaugh, Arthur F, Gabay, Cem, MacCarter, Daryl K, Nash, Peter, Takeuchi, Tsutomu, Goss, Sandra L, Rodila, Ramona, Chen, Kun, Kupper, Hartmut, Kalabic, Jasmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604722/
https://www.ncbi.nlm.nih.gov/pubmed/28955494
http://dx.doi.org/10.1136/rmdopen-2017-000465