Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant

A synthetic heroin analog (MorHap) and a synthetic 42 amino acid V2 loop peptide from A/E strain of HIV-1 gp120 envelope protein that was previously used in a successful phase III vaccine trial were constructed as antigens together with liposomes containing monophosphoryl lipid A as an adjuvant, to...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Oscar B., Matyas, Gary R., Rao, Mangala, Peachman, Kristina K., Jalah, Rashmi, Beck, Zoltan, Michael, Nelson L., Rice, Kenner C., Jacobson, Arthur E., Alving, Carl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604742/
https://www.ncbi.nlm.nih.gov/pubmed/29263870
http://dx.doi.org/10.1038/s41541-017-0013-9

Ejemplares similares

Ejemplares similares