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Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effective vaccine, among them: its silent invasion mechani...

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Detalles Bibliográficos
Autores principales: Sanchez Alberti, Andrés, Bivona, Augusto E., Cerny, Natacha, Schulze, Kai, Weißmann, Sebastian, Ebensen, Thomas, Morales, Celina, Padilla, Angel M., Cazorla, Silvia I., Tarleton, Rick L., Guzmán, Carlos A., Malchiodi, Emilio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604744/
https://www.ncbi.nlm.nih.gov/pubmed/29263868
http://dx.doi.org/10.1038/s41541-017-0010-z