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Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection
The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effective vaccine, among them: its silent invasion mechani...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604744/ https://www.ncbi.nlm.nih.gov/pubmed/29263868 http://dx.doi.org/10.1038/s41541-017-0010-z |