Cargando…
Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection
The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effective vaccine, among them: its silent invasion mechani...
Autores principales: | Sanchez Alberti, Andrés, Bivona, Augusto E., Cerny, Natacha, Schulze, Kai, Weißmann, Sebastian, Ebensen, Thomas, Morales, Celina, Padilla, Angel M., Cazorla, Silvia I., Tarleton, Rick L., Guzmán, Carlos A., Malchiodi, Emilio L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604744/ https://www.ncbi.nlm.nih.gov/pubmed/29263868 http://dx.doi.org/10.1038/s41541-017-0010-z |
Ejemplares similares
-
Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi
por: Sanchez Alberti, Andrés, et al.
Publicado: (2020) -
Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine
por: Bivona, Augusto E., et al.
Publicado: (2018) -
Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi
por: Cerny, Natacha, et al.
Publicado: (2020) -
Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis
por: Sülsen, Valeria P., et al.
Publicado: (2019) -
In Vitro, In Vivo, and In Silico Studies of Cumanin Diacetate as
a Potential Drug against Trypanosoma cruzi Infection
por: Sánchez Alberti, Andrés, et al.
Publicado: (2021)