ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints: a novel pathogenic mechanism in chronic arthritis

OBJECTIVE: To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis inflammation. METHODS: Real-time PCR, western blot and ELISA were performed to evaluate NGF, proNGF, their receptor and cytokine expression in synovial tissue and cells of...

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Detalles Bibliográficos
Autores principales: Minnone, Gaetana, Soligo, Marzia, Caiello, Ivan, Prencipe, Giusi, Manni, Luigi, Marafon, Denise Pires, Magni-Manzoni, Silvia, Manzo, Antonio, Benedetti, Fabrizio De, Bracci-Laudiero, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Paediatric Rheumatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604749/
https://www.ncbi.nlm.nih.gov/pubmed/28955492
http://dx.doi.org/10.1136/rmdopen-2017-000441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604749/
https://www.ncbi.nlm.nih.gov/pubmed/28955492
http://dx.doi.org/10.1136/rmdopen-2017-000441

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