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A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and whether this le...

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Detalles Bibliográficos
Autores principales: Cockerham, Leslie R., Yukl, Steven A., Harvill, Kara, Somsouk, Ma, Joshi, Sunil K., Sinclair, Elizabeth, Liegler, Teri, Hoh, Rebecca, Lyons, Sophie, Hunt, Peter W., Rupert, Adam, Sereti, Irini, Morcock, David R., Rhodes, Ajantha, Emson, Claire, Hellerstein, Marc K., Estes, Jacob D., Lewin, Sharon, Deeks, Steven G., Hatano, Hiroyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604865/
https://www.ncbi.nlm.nih.gov/pubmed/28936485
http://dx.doi.org/10.20411/pai.v2i3.207

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