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A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals
BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and whether this le...
Autores principales: | Cockerham, Leslie R., Yukl, Steven A., Harvill, Kara, Somsouk, Ma, Joshi, Sunil K., Sinclair, Elizabeth, Liegler, Teri, Hoh, Rebecca, Lyons, Sophie, Hunt, Peter W., Rupert, Adam, Sereti, Irini, Morcock, David R., Rhodes, Ajantha, Emson, Claire, Hellerstein, Marc K., Estes, Jacob D., Lewin, Sharon, Deeks, Steven G., Hatano, Hiroyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pathogens and Immunity
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604865/ https://www.ncbi.nlm.nih.gov/pubmed/28936485 http://dx.doi.org/10.20411/pai.v2i3.207 |
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