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Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality

INTRODUCTION: We hypothesized that, like apolipoprotein E (APOE), other late-onset Alzheimer's disease (LOAD) genetic susceptibility loci predict mortality. METHODS: We used a weighted genetic risk score (GRS) from 21 non-APOE LOAD risk variants to predict survival in the Adult Changes in Thoug...

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Detalles Bibliográficos
Autores principales:	Mez, Jesse, Marden, Jessica R., Mukherjee, Shubhabrata, Walter, Stefan, Gibbons, Laura E., Gross, Alden L., Zahodne, Laura B., Gilsanz, Paola, Brewster, Paul, Nho, Kwangsik, Crane, Paul K., Larson, Eric B., Glymour, M. Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604953/ https://www.ncbi.nlm.nih.gov/pubmed/28983503 http://dx.doi.org/10.1016/j.dadm.2017.07.002

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