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Bifurcation kinetics of drug uptake by Gram-negative bacteria
Cell envelopes of many bacteria consist of two membranes studded with efflux transporters. Such organization protects bacteria from the environment and gives rise to multidrug resistance. We report a kinetic model that accurately describes the permeation properties of this system. The model predicts...
Autores principales: | Westfall, David A., Krishnamoorthy, Ganesh, Wolloscheck, David, Sarkar, Rupa, Zgurskaya, Helen I., Rybenkov, Valentin V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604995/ https://www.ncbi.nlm.nih.gov/pubmed/28926596 http://dx.doi.org/10.1371/journal.pone.0184671 |
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