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Autoimmune disease mouse model exhibits pulmonary arterial hypertension

BACKGROUND: Pulmonary arterial hypertension is often associated with connective tissue disease. Although there are some animal models of pulmonary hypertension, an autoimmune disease-based model has not yet been reported. MRL/lpr mice, which have hypergammaglobulinemia, produce various autoimmune an...

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Detalles Bibliográficos
Autores principales: Sugimoto, Koichi, Nakazato, Kazuhiko, Sato, Akihiko, Suzuki, Satoshi, Yoshihisa, Akiomi, Machida, Takeshi, Saitoh, Shu-ichi, Sekine, Hideharu, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605000/
https://www.ncbi.nlm.nih.gov/pubmed/28926602
http://dx.doi.org/10.1371/journal.pone.0184990