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Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death

Introduction Brain death (BD) is the irreversible termination of the functioning of the brain. The diagnosis should be first made by clinical criteria and confirmed by using paraclinical confirmatory techniques (ancillary tests). While conventional brain angiography remains the standard method of ch...

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Autores principales: Sadeghian, Homa, Raeisi, Mohammad Ali, Dolati, Parviz, Motiei-Langroudi, Rouzbeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605121/
https://www.ncbi.nlm.nih.gov/pubmed/28944130
http://dx.doi.org/10.7759/cureus.1491
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author Sadeghian, Homa
Raeisi, Mohammad Ali
Dolati, Parviz
Motiei-Langroudi, Rouzbeh
author_facet Sadeghian, Homa
Raeisi, Mohammad Ali
Dolati, Parviz
Motiei-Langroudi, Rouzbeh
author_sort Sadeghian, Homa
collection PubMed
description Introduction Brain death (BD) is the irreversible termination of the functioning of the brain. The diagnosis should be first made by clinical criteria and confirmed by using paraclinical confirmatory techniques (ancillary tests). While conventional brain angiography remains the standard method of choice, computed tomography angiography (CTA) has emerged as an alternative method. In this study, we tried to evaluate the accuracy of CTA for the diagnosis of BD. Methods In this study, we included nine patients with a clinical diagnosis of BD, confirmed by electroencephalography (EEG). CTA was then performed to compare the results. Results The most frequent cause for BD was multiple trauma (7/9) in our patients, followed by aneurysm rupture and brain infarct. CTA examination in all patients showed opacification of extracranial arteries and major branches of external carotid artery (ECA), including superficial temporal arteries (STAs), while no opacification was observed in the internal carotid arteries (ICA) including and beyond the cavernous segment, middle cerebral arteries (MCAs), anterior cerebral arteries (ACAs), distal vertebral arteries (VAs), and basilar artery (BA). Moreover, no opacification was observed in the internal cerebral veins (ICVs) or great cerebral vein (GCV). Conclusion The accuracy rate of CTA in the detection of intracranial circulatory arrest was 100%. CTA examinations confirmed BD diagnoses in all patients who had clinical and EEG BD diagnoses, and no confliction between CTA findings and clinical diagnoses was observed.
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spelling pubmed-56051212017-09-22 Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death Sadeghian, Homa Raeisi, Mohammad Ali Dolati, Parviz Motiei-Langroudi, Rouzbeh Cureus Neurosurgery Introduction Brain death (BD) is the irreversible termination of the functioning of the brain. The diagnosis should be first made by clinical criteria and confirmed by using paraclinical confirmatory techniques (ancillary tests). While conventional brain angiography remains the standard method of choice, computed tomography angiography (CTA) has emerged as an alternative method. In this study, we tried to evaluate the accuracy of CTA for the diagnosis of BD. Methods In this study, we included nine patients with a clinical diagnosis of BD, confirmed by electroencephalography (EEG). CTA was then performed to compare the results. Results The most frequent cause for BD was multiple trauma (7/9) in our patients, followed by aneurysm rupture and brain infarct. CTA examination in all patients showed opacification of extracranial arteries and major branches of external carotid artery (ECA), including superficial temporal arteries (STAs), while no opacification was observed in the internal carotid arteries (ICA) including and beyond the cavernous segment, middle cerebral arteries (MCAs), anterior cerebral arteries (ACAs), distal vertebral arteries (VAs), and basilar artery (BA). Moreover, no opacification was observed in the internal cerebral veins (ICVs) or great cerebral vein (GCV). Conclusion The accuracy rate of CTA in the detection of intracranial circulatory arrest was 100%. CTA examinations confirmed BD diagnoses in all patients who had clinical and EEG BD diagnoses, and no confliction between CTA findings and clinical diagnoses was observed. Cureus 2017-07-19 /pmc/articles/PMC5605121/ /pubmed/28944130 http://dx.doi.org/10.7759/cureus.1491 Text en Copyright © 2017, Sadeghian et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Sadeghian, Homa
Raeisi, Mohammad Ali
Dolati, Parviz
Motiei-Langroudi, Rouzbeh
Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title_full Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title_fullStr Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title_full_unstemmed Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title_short Brain Computed Tomography Angiography as an Ancillary Test in the Confirmation of Brain Death
title_sort brain computed tomography angiography as an ancillary test in the confirmation of brain death
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605121/
https://www.ncbi.nlm.nih.gov/pubmed/28944130
http://dx.doi.org/10.7759/cureus.1491
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