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Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104

The kinesin-3 family member Unc-104/KIF1A is required for axonal transport of many presynaptic components to synapses, and mutation of this gene results in synaptic dysfunction in mice, flies and worms. Our studies at the Drosophila neuromuscular junction indicate that many synaptic defects in unc-1...

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Detalles Bibliográficos
Autores principales:	Li, Jiaxing, Zhang, Yao V, Asghari Adib, Elham, Stanchev, Doychin T, Xiong, Xin, Klinedinst, Susan, Soppina, Pushpanjali, Jahn, Thomas Robert, Hume, Richard I, Rasse, Tobias M, Collins, Catherine A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605197/ https://www.ncbi.nlm.nih.gov/pubmed/28925357 http://dx.doi.org/10.7554/eLife.24271

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