SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

Selenoprotein synthesis requires the co-translational recoding of a UGA(Sec) codon. This process involves an RNA structural element, called Selenocysteine Insertion Sequence (SECIS) and the SECIS binding protein 2 (SBP2). Several selenoprotein mRNAs undergo unusual cap hypermethylation by the trimet...

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Detalles Bibliográficos
Autores principales: Gribling-Burrer, Anne-Sophie, Leichter, Michael, Wurth, Laurence, Huttin, Alexandra, Schlotter, Florence, Troffer-Charlier, Nathalie, Cura, Vincent, Barkats, Martine, Cavarelli, Jean, Massenet, Séverine, Allmang, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605228/
https://www.ncbi.nlm.nih.gov/pubmed/28115638
http://dx.doi.org/10.1093/nar/gkx031

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