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Query-seeded iterative sequence similarity searching improves selectivity 5–20-fold
Iterative similarity search programs, like psiblast, jackhmmer, and psisearch, are much more sensitive than pairwise similarity search methods like blast and ssearch because they build a position specific scoring model (a PSSM or HMM) that captures the pattern of sequence conservation characteristic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605230/ https://www.ncbi.nlm.nih.gov/pubmed/27923999 http://dx.doi.org/10.1093/nar/gkw1207 |