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Spatial confinement induces hairpins in nicked circular DNA

In living cells, DNA is highly confined in space with the help of condensing agents, DNA binding proteins and high levels of supercoiling. Due to challenges associated with experimentally studying DNA under confinement, little is known about the impact of spatial confinement on the local structure o...

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Detalles Bibliográficos
Autores principales: Japaridze, Aleksandre, Orlandini, Enzo, Smith, Kathleen Beth, Gmür, Lucas, Valle, Francesco, Micheletti, Cristian, Dietler, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605231/
https://www.ncbi.nlm.nih.gov/pubmed/28201616
http://dx.doi.org/10.1093/nar/gkx098

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