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Spatial confinement induces hairpins in nicked circular DNA
In living cells, DNA is highly confined in space with the help of condensing agents, DNA binding proteins and high levels of supercoiling. Due to challenges associated with experimentally studying DNA under confinement, little is known about the impact of spatial confinement on the local structure o...
Autores principales: | Japaridze, Aleksandre, Orlandini, Enzo, Smith, Kathleen Beth, Gmür, Lucas, Valle, Francesco, Micheletti, Cristian, Dietler, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605231/ https://www.ncbi.nlm.nih.gov/pubmed/28201616 http://dx.doi.org/10.1093/nar/gkx098 |
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