Cargando…

High-throughput single-molecule mapping links subtelomeric variants and long-range haplotypes with specific telomeres

Accurate maps and DNA sequences for human subtelomere regions, along with detailed knowledge of subtelomere variation and long-range telomere-terminal haplotypes in individuals, are critical for understanding telomere function and its roles in human biology. Here, we use a highly automated whole gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Young, Eleanor, Pastor, Steven, Rajagopalan, Ramakrishnan, McCaffrey, Jennifer, Sibert, Justin, Mak, Angel C.Y., Kwok, Pui-Yan, Riethman, Harold, Xiao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605236/ https://www.ncbi.nlm.nih.gov/pubmed/28180280 http://dx.doi.org/10.1093/nar/gkx017

Ejemplares similares

High-throughput single-molecule telomere characterization
por: McCaffrey, Jennifer, et al.
Publicado: (2017)

CRISPR-CAS9 D10A nickase target-specific fluorescent labeling of double strand DNA for whole genome mapping and structural variation analysis
por: McCaffrey, Jennifer, et al.
Publicado: (2016)

Single-molecule analysis of subtelomeres and telomeres in Alternative Lengthening of Telomeres (ALT) cells
por: Abid, Heba Z., et al.
Publicado: (2020)

Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping
por: Turner, Daniel J., et al.
Publicado: (2008)

Comprehensive Analysis of Human Subtelomeres by Whole Genome Mapping
por: Young, Eleanor, et al.
Publicado: (2020)

Human subtelomeric duplicon structure and organization
por: Ambrosini, Anthony, et al.
Publicado: (2007)

Customized optical mapping by CRISPR–Cas9 mediated DNA labeling with multiple sgRNAs
por: Abid, Heba Z, et al.
Publicado: (2020)

Detection of alternative lengthening of telomeres by telomere quantitative PCR
por: Lau, Loretta M. S., et al.
Publicado: (2013)

Haplotype diversity and sequence heterogeneity of human telomeres
por: Grigorev, Kirill, et al.
Publicado: (2021)

Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example
por: Pont-Kingdon, Genevieve, et al.
Publicado: (2005)

NPGREAT: assembly of human subtelomere regions with the use of ultralong nanopore reads and linked-reads
por: Adam, Eleni, et al.
Publicado: (2022)

An efficient method for multi-locus molecular haplotyping
por: Konfortov, Bernard A., et al.
Publicado: (2007)

Accurate detection for a wide range of mutation and editing sites of microRNAs from small RNA high-throughput sequencing profiles
por: Zheng, Yun, et al.
Publicado: (2016)

The telomere lengthening conundrum—artifact or biology?
por: Steenstrup, Troels, et al.
Publicado: (2013)

SNP-specific extraction of haplotype-resolved targeted genomic regions
por: Dapprich, Johannes, et al.
Publicado: (2008)

An accurate clone-based haplotyping method by overlapping pool sequencing
por: Li, Cheng, et al.
Publicado: (2016)

Shotgun haplotyping: a novel method for surveying allelic sequence variation
por: Lindsay, Sarah J., et al.
Publicado: (2005)

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations
por: Giallonardo, Francesca Di, et al.
Publicado: (2014)

Chromosome-scale mega-haplotypes enable digital karyotyping of cancer aneuploidy
por: Bell, John M., et al.
Publicado: (2017)

Measurement of telomere DNA content by dot blot analysis
por: Kimura, Masayuki, et al.
Publicado: (2011)

In situ visualization of telomere elongation patterns in human cells
por: Diolaiti, Morgan E., et al.
Publicado: (2013)

Fluorescence spectroscopic detection and measurement of single telomere molecules
por: Beh, Cyrus W, et al.
Publicado: (2018)

Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting
por: Nedelkova, Marta, et al.
Publicado: (2011)

Frequency-based haplotype reconstruction from deep sequencing data of bacterial populations
por: Pulido-Tamayo, Sergio, et al.
Publicado: (2015)

Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules
por: Redin, David, et al.
Publicado: (2017)

Estimating telomere length from whole genome sequence data
por: Ding, Zhihao, et al.
Publicado: (2014)

Scoring schemes of palindrome clusters for more sensitive prediction of replication origins in herpesviruses
por: Chew, David S. H., et al.
Publicado: (2005)

Analysis of the epigenetic status of telomeres by using ChIP-seq data
por: Vaquero-Sedas, María I., et al.
Publicado: (2012)

The dynamics of forming a triplex in an artificial telomere inferred by DNA mechanics
por: Li, Ning, et al.
Publicado: (2019)

Single-cell genome-wide concurrent haplotyping and copy-number profiling through genotyping-by-sequencing
por: Masset, Heleen, et al.
Publicado: (2022)

A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays
por: Ning, Kang, et al.
Publicado: (2005)

Nanoliter high throughput quantitative PCR
por: Morrison, Tom, et al.
Publicado: (2006)

Analyzing editosome function in high-throughput
por: Del Campo, Cristian, et al.
Publicado: (2020)

Quantitative telomeric overhang determination using a double-strand specific nuclease
por: Zhao, Yong, et al.
Publicado: (2008)

Telomere length measurement by a novel monochrome multiplex quantitative PCR method
por: Cawthon, Richard M.
Publicado: (2009)

IDP-ASE: haplotyping and quantifying allele-specific expression at the gene and gene isoform level by hybrid sequencing
por: Deonovic, Benjamin, et al.
Publicado: (2017)

Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing
por: Yu, Jiaying, et al.
Publicado: (2020)

Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction
por: Knyazev, Sergey, et al.
Publicado: (2021)

High-throughput methods for measuring DNA thermodynamics
por: Bae, Jin H, et al.
Publicado: (2020)

ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats
por: Frank, Lukas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r40i58hrg2d4depad0p2aee4sh