Cargando…

Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase

The five human RecQ helicases participate in multiple processes required to maintain genome integrity. Of these, the disease-linked RecQ4 is the least studied because it poses many technical challenges. We previously demonstrated that the yeast Hrq1 helicase displays similar functions to RecQ4 in vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers, Cody M., Wang, Joseph Che-Yen, Noguchi, Hiroki, Imasaki, Tsuyoshi, Takagi, Yuichiro, Bochman, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605238/
https://www.ncbi.nlm.nih.gov/pubmed/28334827
http://dx.doi.org/10.1093/nar/gkx151