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Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase
The five human RecQ helicases participate in multiple processes required to maintain genome integrity. Of these, the disease-linked RecQ4 is the least studied because it poses many technical challenges. We previously demonstrated that the yeast Hrq1 helicase displays similar functions to RecQ4 in vi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605238/ https://www.ncbi.nlm.nih.gov/pubmed/28334827 http://dx.doi.org/10.1093/nar/gkx151 |