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Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy

The full-length translation-regulating add adenine riboswitch (Asw) from Vibrio vulnificus has a more complex conformational space than its isolated aptamer domain. In addition to the predicted apo (apoA) and holo conformation that feature the conserved three-way junctional purine riboswitch aptamer...

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Detalles Bibliográficos
Autores principales:	Warhaut, Sven, Mertinkus, Klara Rebecca, Höllthaler, Philipp, Fürtig, Boris, Heilemann, Mike, Hengesbach, Martin, Schwalbe, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605240/ https://www.ncbi.nlm.nih.gov/pubmed/28204648 http://dx.doi.org/10.1093/nar/gkx110

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