Cargando…

RNA helicase DDX19 stabilizes ribosomal elongation and termination complexes

The human DEAD-box RNA-helicase DDX19 functions in mRNA export through the nuclear pore complex. The yeast homolog of this protein, Dbp5, has been reported to participate in translation termination. Using a reconstituted mammalian in vitro translation system, we show that the human protein DDX19 is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mikhailova, Tatiana, Shuvalova, Ekaterina, Ivanov, Alexander, Susorov, Denis, Shuvalov, Alexey, Kolosov, Peter M., Alkalaeva, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605241/ https://www.ncbi.nlm.nih.gov/pubmed/28180304 http://dx.doi.org/10.1093/nar/gkw1239

Ejemplares similares

PABP enhances release factor recruitment and stop codon recognition during translation termination
por: Ivanov, Alexandr, et al.
Publicado: (2016)

Stabilization of eukaryotic ribosomal termination complexes by deacylated tRNA
por: Susorov, Denis, et al.
Publicado: (2015)

eIF3j facilitates loading of release factors into the ribosome
por: Egorova, Tatiana, et al.
Publicado: (2021)

Method for Rapid Analysis of Mutant RNA Polymerase Activity on Templates Containing Unnatural Nucleotides
por: Egorova, Tatiana, et al.
Publicado: (2021)

Discovery of a novel role of tumor suppressor PDCD4 in stimulation of translation termination
por: Shuvalova, Ekaterina, et al.
Publicado: (2021)

Upstream Open Reading Frames Located in the Leader of Protein Kinase Mζ mRNA Regulate Its Translation
por: Bal, Natalia V., et al.
Publicado: (2016)

NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47
por: Sekiguchi, Takeshi, et al.
Publicado: (2006)

eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast
por: Mohammad, Mahabub Pasha, et al.
Publicado: (2021)

In vivo evidence that eIF3 stays bound to ribosomes elongating and terminating on short upstream ORFs to promote reinitiation
por: Mohammad, Mahabub Pasha, et al.
Publicado: (2017)

Redundant role of DEAD box proteins p68 (Ddx5) and p72/p82 (Ddx17) in ribosome biogenesis and cell proliferation
por: Jalal, Carolin, et al.
Publicado: (2007)

Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongation
por: Van Dyke, Natalya, et al.
Publicado: (2009)

Estimation of peptide elongation times from ribosome profiling spectra
por: Pavlov, Michael Y, et al.
Publicado: (2021)

The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)
por: Hirokawa, Go, et al.
Publicado: (2008)

A single amino acid change of translation termination factor eRF1 switches between bipotent and omnipotent stop-codon specificity(†)
por: Eliseev, Boris, et al.
Publicado: (2011)

Distinct types of translation termination generate substrates for ribosome-associated quality control
por: Shcherbik, Natalia, et al.
Publicado: (2016)

The ATP-dependent RNA helicase, DDX42 interacts with paxillin and regulates apoptosis and polarization of Ba/F3 cells
por: Sohn, Sung Oh, et al.
Publicado: (2019)

Ribosomal stress activates eEF2K–eEF2 pathway causing translation elongation inhibition and recruitment of Terminal Oligopyrimidine (TOP) mRNAs on polysomes
por: Gismondi, Angelo, et al.
Publicado: (2014)

The amino terminal end determines the stability and assembling capacity of eukaryotic ribosomal stalk proteins P1 and P2
por: Camargo, Hendricka, et al.
Publicado: (2011)

The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits
por: Fernández-Pevida, Antonio, et al.
Publicado: (2016)

Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation
por: Biziaev, Nikita, et al.
Publicado: (2022)

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes
por: Geissler, Rene, et al.
Publicado: (2012)

Quantifying the impact of small molecule ligands on G-quadruplex stability against Bloom helicase
por: Maleki, Parastoo, et al.
Publicado: (2019)

Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides
por: Padmanabhan, Prasad Kottayil, et al.
Publicado: (2021)

Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae
por: Jindal, Supriya, et al.
Publicado: (2019)

Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G
por: Mandava, Chandra Sekhar, et al.
Publicado: (2012)

Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel
por: Cridge, Andrew G, et al.
Publicado: (2018)

eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences
por: Pelechano, Vicent, et al.
Publicado: (2017)

The interaction of mammalian mitochondrial translational initiation factor 3 with ribosomes: evolution of terminal extensions in IF3(mt)
por: Haque, Md. Emdadul, et al.
Publicado: (2008)

Carboxy terminal modifications of the P0 protein reveal alternative mechanisms of nuclear ribosomal stalk assembly
por: Francisco-Velilla, Rosario, et al.
Publicado: (2013)

Mechanism of fusidic acid inhibition of RRF- and EF-G-dependent splitting of the bacterial post-termination ribosome
por: Borg, Anneli, et al.
Publicado: (2016)

Structure–function relationship in the ‘termination upstream ribosomal binding site’ of the calicivirus rabbit hemorrhagic disease virus
por: Wennesz, René, et al.
Publicado: (2019)

The DDX6–4E-T interaction mediates translational repression and P-body assembly
por: Kamenska, Anastasiia, et al.
Publicado: (2016)

Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis
por: Ioannou, Charikleia, et al.
Publicado: (2006)

Monosomes buffer translational stress to allow for active ribosome elongation
por: Schieweck, Rico, et al.
Publicado: (2023)

DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs
por: Kukhanova, Marina K., et al.
Publicado: (2020)

The Genome Stability Maintenance DNA Helicase DDX11 and Its Role in Cancer
por: Mahtab, Mohammad, et al.
Publicado: (2021)

Codon usage and protein length-dependent feedback from translation elongation regulates translation initiation and elongation speed
por: Lyu, Xueliang, et al.
Publicado: (2021)

The amino terminal domain from Mrt4 protein can functionally replace the RNA binding domain of the ribosomal P0 protein
por: Rodríguez-Mateos, María, et al.
Publicado: (2009)

Yeast strains with N-terminally truncated ribosomal protein S5: implications for the evolution, structure and function of the Rps5/Rps7 proteins
por: Lumsden, Thomas, et al.
Publicado: (2010)

Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast
por: Rubio, Angela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_43a59qu6bhrs6sfavkf6nqjoah