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Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells
Latently human immunodeficiency virus (HIV)-infected cells are transcriptionally quiescent and invisible to clearance by the immune system. To demonstrate that the latency reversing agent vorinostat (VOR) induces a window of vulnerability in the latent HIV reservoir, defined as the triggering of vir...
Autores principales: | Sung, Julia A., Sholtis, Katherine, Kirchherr, Jennifer, Kuruc, Joann D., Gay, Cynthia L., Nordstrom, Jeffrey L., Bollard, Catherine M., Archin, Nancie M., Margolis, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605299/ https://www.ncbi.nlm.nih.gov/pubmed/28803740 http://dx.doi.org/10.1016/j.ebiom.2017.07.019 |
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