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Chemical Transport Knockout for Oxidized Vitamin C, Dehydroascorbic Acid, Reveals Its Functions in vivo

Despite its transport by glucose transporters (GLUTs) in vitro, it is unknown whether dehydroascorbic acid (oxidized vitamin C, DHA) has any in vivo function. To investigate, we created a chemical transport knockout model using the vitamin C analog 6-bromo-ascorbate. This analog is transported on so...

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Detalles Bibliográficos
Autores principales:	Tu, Hongbin, Wang, Yu, Li, Hongyan, Brinster, Lauren R., Levine, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605377/ https://www.ncbi.nlm.nih.gov/pubmed/28851583 http://dx.doi.org/10.1016/j.ebiom.2017.08.017

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