Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese

OBJECTIVE: Type 1 diabetes (T1D) is known to be caused by Th1 cell-dependent autoimmunity. Recently, we reported that TYK2 promoter variant serves as a putative virus-induced diabetes susceptibility gene associated with deteriorated interferon-dependent antiviral response. TYK2 is also related to HI...

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Detalles Bibliográficos
Autores principales: Mine, Keiichiro, Hirakawa, Kanako, Kondo, Shiori, Minami, Masae, Okada, Akira, Tsutsu, Nobutaka, Yokogawa, Yasushi, Hibio, Yumi, Kojima, Fumiko, Fujimoto, Shuji, Kurisaki, Hironori, Anzai, Keizo, Yoshikai, Yasunobu, Nagafuchi, Seiho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605380/
https://www.ncbi.nlm.nih.gov/pubmed/28826655
http://dx.doi.org/10.1016/j.ebiom.2017.08.012

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